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Karthus

Karthus Build & Runes

Death Defied
P
Lay Waste
Q
Wall of Pain
W
Defile
E
Requiem
R

Karthus with Blitz's best data for every build. The highest win rate Karthus build, from rune set to skill order to item path, for One For All. LoL Patch 14.8

vsKai'Sa

Second Skin
P
Icathian Rain
Q
Void Seeker
W
Supercharge
E
Killer Instinct
R
No Builds Found

Karthus Guide

Learn Karthus with our Karthus guide. Learn about Karthus's strengths and Karthus's weaknesses, and harness key insights to optimize your playstyle. Whether you're a seasoned player or new to Karthus, our guide provides the tools you need to dominate the battlefield.
Key Insights
  • If
    Karthus
    Q
    only hits one enemy, it deals double damage.
  • Karthus
    Q
    and
    Karthus
    W
    reveal their affected areas.
  • Karthus
    E
    deals an extra tick of damage when Karthus recasts it.
  • Karthus
    R
    damages all targetable enemy champions.
Strengths
  • Even if Karthus is killed first, he continues fighting with
    Karthus
    P
    , giving his team an advantage in fights since enemy resources were used on him.
  • Forces enemies to play with a "lower HP bar" since he can cast
    Karthus
    R
    at any point to finish them off.
  • Best with items enhancing magic damage, penetration, and burst potential.
Weaknesses
  • Completely immobile, leaving him vulnerable to ganks.
  • When fighting, if Karthus misses a single
    Karthus
    Q
    , it becomes much harder to land one.
  • Vulnerable to items that mitigate magic damage or negate spell effects, aiding in reducing the impact of his
    Karthus
    R
    .